Pull together

Myosins pull together—separately

D on’t tell your high school football coach, but it is possible to have teamwork even if nobody’s in charge. Inside a cell, for example, myosin VI motors work in concert to haul cargoes along the actin cytoskeleton, Sivaramakrishnan and Spudich reveal (1). Instead of providing muscle power, myosin VI is one of the unconventional myosins whose job is intracellular transportation. Researchers hav...

Flagellar Motility: All Pull Together

Eukaryotic flagella produce a swimming force by coordinating thousands of dynein motor proteins. Recent work provides new clues into how this coordination is achieved.

The Semantic Web and Expert Metadata: Pull Apart Then Bring Together

Rehabilitation management of low back pain – it’s time to pull it all together!

In the past, rehabilitation research initiatives for low back pain (LBP) have targeted outcome enhancement through personalized treatment approaches, namely through classification systems (CS). Although the use of CS has enhanced outcomes, common management practices have not changed, the prevalence of LBP is still high, and only selected patients meet the CS profile, namely those with a nocice...

To Pull or Not to Pull: What Is the Question?

The terms pull and lean production have become cornerstones of modern manufacturing practice. But, although they are widely used, they are less widely understood. In this paper, we argue that while the academic literature has steadily revealed the richness of the pull/lean concepts, the practitioner literature has progressively simplified these terms to the point where serious misunderstandings...